Her family members are called home from abroad due to the severity of the situation. She is discharged with GDC-0199 chemical structure the newborn 14 days after delivery.
She is never informed about the fact that she is treated with off-label medication. The family is not informed about their right to complain to the National Patient Complaint System and they are not informed about the possibility to seek compensation for the poor outcome (damaged uterus and a child with lifelong disability) from the Patient Complaint System  and . Furthermore these cases (mother and baby) were not reported as an adverse incident report. After a public debate in 2012 on unreported side effects to misoprostol this family brought their case to the Patient Compensation Association and the child received a substantial economic compensation. The Patient Compensations Association stated that it was highly probable that misoprostol was the cause for these adverse events. Misoprostol is a prostaglandin E1 analog and very efficient uterotonic buy Dorsomorphin drug . The US Food and Drug Administration (FDA) has listed a range of side effects such as hyperstimulation, uterine tetany, meconium-stained amniotic fluid, uterine rupture,
maternal shock, maternal death, fetal bradycardia and fetal death . Though both mother and child survived, this parturition included hyperstimulation, uterine rupture, meconium-stained amniotic fluid, life-threatening maternal hemorrhage, fetal bradycardia and threatening fetal death. This woman previously had an uncomplicated vaginal delivery, and her current pregnancy was uneventful. It is highly unlikely to experience a uterine rupture in birth without a previously scarred uterus . However high parity, malpresentation or placental abruption are predisposing factors ,  and . External force to the maternal abdomen (i.e. Kristeller-maneuver, vacuum- or forceps assisted birth) can, in rare cases, cause rupture of an unscarred uterus ,  and . None of these factors were present in this case. 25 μg misoprostol used vaginally is the recommended dose according Etomidate to the Cochrane
review . Prostaglandins and other uterotonic agents can cause uterine rupture , ,  and . Several studies have found misoprostol more prone to hyperstimulation with fetal heart rate changes, meconium stained amniotic liquid and uterine rupture than other uterotonic agents  and  and reports on uterine rupture on previously unscarred uterus after misoprostol induction has been reported , , , ,  and . This birth was induced by misoprostol and thus not spontaneous. The woman experienced frequent contractions (5 in 10 min), which suggests hyperstimulation. The rapid progress of labor, her cervix dilated from 3–4 cm to 9 cm within 25 min and the fast decent of the fetal head from pelvic brim to below the ischial spines ads further to this argument.