44 years among women in 2009. Japan may be one of the most eminent
countries where many SBI-0206965 clinical trial people live to an advanced age because more than 50% of Japanese people survive over 80 years. As average life expectancy lengthens, the number of geriatric patients who need emergency abdominal surgery will increase. Compared with elective surgery, emergency abdominal surgery is associated with increased morbidity and mortality, especially in elderly patients [1–6]. Thus, elderly patients with abdominal surgical emergency may be at risk for severe and life-threatening conditions because of medical Ferrostatin-1 manufacturer comorbidities, insufficient screening, unrecognized symptoms, and inadequate overall access to the health care system . In this study, geriatric patients were limited to those aged 80 years or older because of increasing life expectancy in Japanese people. The aim of the
present study was to report our experience with emergency abdominal surgery in the elderly patients and to identify risk factors that have an impact on mortality in these patients. Methods Ninety-four patients ages 80 years PF-01367338 nmr or over who underwent emergency surgery for acute abdominal disease at our institutions between 2001 and 2010 were enrolled in this study. They included 36 men (38.3%) and 58 women (61.7%) ages 80–104 years (mean, 85.6 years). Of the 94 patients, 71 (75.5%) had co-existing medical diseases such as hypertension in 44 patients (46.8%), chronic heart disease in 17 (18.1%), chronic obstructive pulmonary disease (COPD) in 14 (14.9%), cerebrovascular disease and DM in 11 (11.7%) respectively, chronic renal failure in 6 (6.4%), and others in 12 (12.8%). Of the 71 patients with concomitant medical disease, 32 had 1 medical disease and 39 had 2 or more additional medical problems. The Eastern Cooperative Oncology over Group (ECOG) performance status score , which reflects the daily living abilities of the patient was estimated for these patients and the results were as follows: 2 patients were with grade 0, 28 with grade
1, 48 with grade 2, 13 with grade 3, and 3 with grade 4 (Table 1). Of the 94 patients, 76 (80.9%) underwent emergency surgery within 48 hours after admission. The other18 patients (e.g., those with acute cholecystitis, intestinal obstruction due to adhesion) were first treated conservatively, and only when the conservative treatment failed did they undergo surgery. Table 1 Of the 94 patients, 71 (75.5%) had co-existing medical diseases such as hypertension in 44 patients (46.8%), chronic heart disease in 17 (18.1%), chronic obstructive pulmonary disease (COPD) in 14 (14.9%), cerebrovascular disease and DM in 11 (11.7%) respectively, chronic renal failure in 6 (6.4%), and others in 12 (12.8%) Variables n (%) Age 80-104 years (mean: 85.6) Gender Male 36 (38.3%) Female 58 (61.7%) Co-existing medical disease Hypertension 44 (46.8%) Chronic heart disease 17 (18.1%) COPD 14 (14.9%) Cerebrovascular disease 11 (11.7%) DM 11 (11.7%) Chronic renal failure 6 (6.