Author Archives: admin

Various chemokine receptors, cytokine receptors, and pattern reco

Various chemokine receptors, cytokine receptors, and pattern recognition receptors are expressed by γδ T cells and these receptors have been shown to be involved in the activation of γδ T cells, especially for the induction of IL-17 (Fig. 1). IL-1, … Continue reading

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The PDN and the combined PDN + taurine treatments have a similar

The PDN and the combined PDN + taurine treatments have a similar effect on both histology and plasma enzyme profile. Then, we verified the real occurrence of a modification in taurine content in target tissues of animals undergoing the combined treatment. The … Continue reading

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We considered that this problem could be overcome by the eventual

We considered that this problem could be overcome by the eventual demise of plasma cells, alone or in combination with B cell depletion. However, plasma cells have very long half-lives, measured in months or even years [11]. Finally, in this … Continue reading

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Methods: Thoracic aortas removed from 10-week-old male Sprague-Da

Methods: Thoracic aortas removed from 10-week-old male Sprague-Dawley rats were cut into 3- to 5-mm rings and were cultured for 10 days. Phosphate concentration was titrated in the medium to induce vascular calcification. Ferric citrate was applied as an iron donor … Continue reading

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The hippocampus is particularly susceptible to perinatal HII (Nya

The hippocampus is particularly susceptible to perinatal HII (Nyakas, Buwalda, & Luiten, 1996). Many previous animal and human studies have demonstrated atrophy of the hippocampus and memory impairments following HII (Isaacs et al., 2003; Maneru et al., 2003; Mikati et al., 2005; Quamme, … Continue reading

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Sequencing of hotspot mutations and fluorescence in situ hybridiz

Sequencing of hotspot mutations and fluorescence in situ hybridization of relevant genes were undertaken. Median age at diagnosis of six patients was 7.6 years. Tumours originated in the cerebral cortex (n = 2) or diencephalon (n = 4). Three patients presented with acute, Idelalisib … Continue reading

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In support of this hypothesis, they found that stimulation of DCs

In support of this hypothesis, they found that stimulation of DCs with MSU caused upregulation of p21, which is protective against p53-driven cell death in Nlrp3−/− cells, but not WT DCs. Furthermore, WT DCs exhibited a significant increase in MSU-induced … Continue reading

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When directly comparing the changes in Treg frequencies due to tr

When directly comparing the changes in Treg frequencies due to transmigration between patients with RR-MS and HD, we found that transendothelial Treg migration in our cohort of Selleckchem Crizotinib patients with MS was significantly impaired under basal conditions, but could … Continue reading

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Antifungal–drug interactions that involve CYP-mediated biotransfo

Antifungal–drug interactions that involve CYP-mediated biotransformation of other medications are summarised in Table 1. For a more detailed discussion of drug interactions between mould-active azoles and medicines in general, the reader is referred to more comprehensive reviews.60,61 Interactions involving azoles and … Continue reading

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We also found that the three dyads that showed longer language pa

We also found that the three dyads that showed longer language patterns were also those more capable of symmetry. The role of language in the development of joint engagement has also been underlined by Brinck and Gärdenfors (2003). According to … Continue reading

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