Patients

Patients Tenatoprazole? who had severe injuries with a potential need for intensive care and who had spontaneous circulation on admission, were included. In contrast to the GRR, patients with burns, drowning, poisoning and preclinical deaths were excluded. Data were documented within the TR-DGU via a password-protected online program with multiple plausibility and completeness checks. Participating hospitals received extended annual audit reports in which results were compared across institutions. More than 200 hospitals are currently participating in this registry, providing about 10,000 patients per year. The Trauma Registry is organized by the DGU. Due to the anonymity of data collection and the fact that the primary purpose of the registry is quality control, patient consent was not necessary.

For the present analysis, 1,535 patients with early CPR were included. The inclusion criteria were as follows: primarily admission from the pre-hospital site of injury; Injury Severity Score (ISS) of nine points or more; admission to a hospital in Germany; available data about pre-hospital and early in-hospital CPR attempts (performed/not performed); year of injury from 1993 to 2009. Of included patients, 814 received pre-hospital CPR, while 989 patients experienced cardiac arrest during the early in-hospital phase before ICU admission, and 268 patients had both pre-hospital and in-hospital CPR attempts. A total of 25,366 patients from the TR-DGU with the same inclusion criteria, but without any CPR attempts, served as a ‘trauma control group’ (group E).

Patients from the TR-DGU were divided into the following three groups:? group ATR-DGU: pre-hospital CPR and ATH (n = 814)? group D: trauma control group without any CPR (n = 25,366)Group ATR-DGU from the TR-DGU corresponds to group AGRR from the GRR, which lists patients who were admitted to a hospital with circulation after cardiac arrest.The GRR represents all patients with any pre-hospital cardiac arrest at the participating centers who received CPR treatment by emergency medical doctors, independently of ROSC. TR-DGU represents only patients with severe trauma who reached hospital with spontaneous circulation. Due to data security and confidentiality, there is no information available about whether or not individual patients were included in both registries in parallel.

As the GRR does not provide any information about the in-hospital treatment and outcome after cardiac arrest and the TR-DGU is limited to trauma patients who had spontaneous circulation GSK-3 at hospital admission but does not contain data of patients who died at the scene, we combined data from these two large national registries in this study to analyze the mid-term outcome of CPR after traumatic cardiac arrest in Germany.StatisticsData are presented as means �� standard deviation (SD) for continuous variables and as percentages for categorical variables.

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