Setting: Atlanta, GA.
Practice description: RA consists of a staff of nine members, three of whom are pharmacists. The mission of RA is to support CDC’s preparedness and emergency response activities and to ensure regulatory compliance for critical medical countermeasures against potential threats from natural, chemical, biological, radiological,
or nuclear events.
Conclusion: RA was well involved in the response to the H1N1 outbreak through numerous activities, GSK1838705A order such as submitting multiple Emergency Use Authorization (EUA) requests to the Food and Drug Administration, including those for medical countermeasures to be deployed from the Strategic National Stockpile, and developing the CDC EUA website (www.cdc.gov/h1n1flu/eua). RA will continue to support current and future preparedness and emergency response activities by ensuring that the appropriate regulatory mechanisms are in place for the deployment of critical medical countermeasures from the Strategic National Stockpile against threats to public health.”
“MicroRNAs
(miRNAs) are small noncoding RNAs, approximately 22 nucleotides in length, found in diverse organisms. They have emerged in recent years as key regulators of a broad spectrum of cellular functions. miRNAs regulate biological processes by inducing translational inhibition and degradation of their target mRNAs through base pairing to partially or fully complementary sites. In the field of miRNA research, the identification of the targets of individual S3I-201 miRNAs is of utmost importance. Our understanding of the molecular mechanisms by which individual find more miRNAs modulate cellular functions will remain incomplete until a full set of miRNA targets is identified and validated. Since a miRNA may regulate many of its targets at the translational level without affecting mRNA abundance, proteomic methods are best suited
for revealing the full spectrum of miRNA targets. Quantitative proteomics is emerging as a powerful toolbox for identifying miRNA targets and for quantifying the contribution of translational repression by miRNAs. In this review, the authors summarize the quantitative proteomic approaches that have been employed for identification of miRNA targets and discuss current challenges as well as possible ways of overcoming them.”
“Objectives: To (1) determine the public’s current method of medication disposal, (2) identify the public’s knowledge of the environmental impact of inappropriate medication disposal, (3) determine whether student-facilitated education improves the public’s awareness of safe medication disposal, and (4) determine whether the public recognizes student pharmacists as a public health information resource for issues such as safe disposal of medications.
Design: Cross sectional.
Setting: Albany, NY, pharmacies during August and September 2009.