That information was ascertained and obtained from the official vaccination document of each child during the mother’s interview. To investigate associations a chi-square (χ2) test was used. To adjust for the confounding variables, multivariate analysis was performed using “stepwise forward” technique. The selection criteria for inclusion
in the final logistic model were association with incomplete vaccination with p < 0.20. A level of p < 0.05 was chosen to indicate statistically significant association. Population attributable rate (PAR%) was calculated to identify Selleck Proteasome inhibitor the proportion of incomplete vaccination attributable to each risk factor (p < 0.100). Children with nutritional disorders or incomplete vaccination were referred
to outpatient care in the Department of Paediatrics of the Universidade Federal de São Paulo. The study was approved by the ethics and research committee of the same selleck kinase inhibitor University. We found that 10.9% (CI 95%: 7.3–15.3%) of the children had incomplete vaccination. Table 1 presents the prevalence of incomplete vaccination in children according to risk factors and the PAR%. Children born prematurely were 4 times more likely to have incomplete vaccination (p = 0.004) and the attributable proportion was 20.2%. Children had malnutrition, had siblings less than five years of age and living at inadequate housing also presented higher risks to incomplete vaccination, showing attributable proportion between for 8.1 and 29.4. Fig. 2 presents the multiple logistic model for risk factors for incomplete vaccination (p = 0.0028) and PAR% of the four variables that exhibited statistically significant associations controlled for sex and age. Among the socioeconomic variables, living at “inadequate housing” (unsuitable sewerage
system or walls made of wood, indicating being part of a shanty town) was the first identified to compose the logistic model. Of the variables indicating individual child processes, “malnutrition”, “prematurity” and “poor prenatal care” (mother had not attended the minimally recommended four antenatal visits) were also selected to compose the final model. Otherwise, presence of one or more siblings under five years of age, per capita income below half minimum wage, maternal education less than four years, Libraries exclusive breastfeeding less than 120 days, avoidable hospitalization and low birth weight (less than 2.5 kg) attended the selection criteria to compound the logistic model (p < 0.20); however, these were not remained in because they lost their statistical significance when included in the model. Only 4 factors were independently and significantly associated with incomplete vaccination: prematurity, malnutrition, inadequate housing and poor prenatal care. These have PAR% varying from 7 to 20%. The rate of incomplete vaccination have been shown to dependent on characteristics of the studied children  and .