The authors claim full responsibility for the contents of the article. References 1. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, Moorman MA, Simonetti DW, Craig S, Marshak DR: Multilineage potential of adult human mesenchymal stem cells. Science 1999,284(5411):143–147.PubMed 2. Mayhall EA, Paffett-Lugassy N, Zon LI: The clinical potential of stem cells. Curr Opin Cell Biol 2004,16(6):713–720.PubMed 3. Fortier
LA: Stem cells: classifications, controversies, and clinical applications. Vet Surg 2005,34(5):415–423.PubMed 4. Zhong W: Timing cell-fate determination during asymmetric cell divisions. Curr Opin Neurobiol 2008,18(5):472–478.PubMed 5. Doe CQ: Neural stem cells: balancing self-renewal with differentiation. Development 2008,135(9):1575–1587.PubMed 6. Knoblich JA: Mechanisms of asymmetric stem cell division. Cell 2008,132(4):583–597.PubMed 7. Zhong W, Chia W: Neurogenesis and asymmetric cell division. MG-132 datasheet Curr Opin Neurobiol 2008,18(1):4–11.PubMed 8. Baksh D, Song L, Tuan RS: Adult mesenchymal stem cells: characterization, differentiation, and application in cell and AZD1208 clinical trial gene therapy. J Cell Mol Med 2004,8(3):301–316.PubMed 9. Barry FP, Murphy JM:
Mesenchymal stem cells: clinical applications and biological characterization. Int J Biochem Cell Biol 2004,36(4):568–584.PubMed 10. Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiergiel JJ, Marshall VS, Jones JM: Embryonic stem cell lines derived from human blastocysts. Science Chlormezanone 1998,282(5391):1145–1147.PubMed 11. Baharvand H, Ashtiani SK, Valojerdi MR, Shahverdi A, Taee A, Sabour D: Establishment and in vitro differentiation of a
new embryonic stem cell line from human blastocyst. Differentiation 2004,72(5):224–229.PubMed 12. Ladurner P, Rieger R, Baguna J: Spatial distribution and differentiation potential of stem cells in hatchlings and adults in the marine platyhelminth macrostomum sp.: a bromodeoxyuridine analysis. Dev Biol 2000,226(2):231–241.PubMed 13. Fang TC, Alison MR, Wright NA, Poulsom R: Adult stem cell plasticity: will engineered tissues be rejected? Int J Exp Pathol 2004,85(3):115–124.PubMed 14. Pera MF, Reubinoff B, Trounson A: Human embryonic stem cells. J Cell Sci 2000,113(Pt 1):5–10.PubMed 15. Pessina A, Gribaldo L: The key role of adult stem cells: therapeutic perspectives. Curr Med Res Opin 2006,22(11):2287–2300.PubMed 16. Gucciardo L, Lories R, Ochsenbein-Kolble N, Done E, Zwijsen A, Deprest J: Fetal mesenchymal stem cells: isolation, properties and potential use in perinatology and regenerative medicine. BJOG 2009,116(2):166–172.PubMed 17. Blau HM, Brazelton TR, Weimann JM: The evolving concept of a stem cell: entity or function? Cell 2001,105(7):829–841.PubMed 18. Joshi D, Behari M: Neuronal stem cells. Neurol India 2003,51(3):323–328.PubMed 19. Fan J, Varshney RR, Ren L, Cai D, Wang DA: Synovium-derived mesenchymal stem cells: a new cell source for musculoskeletal regeneration.