The results of this trial are consistent with the results of two

The results of this trial are consistent with the results of two other trials that evaluated the use of Kinesio Taping in people with chronic low back pain. One

study16 allocated people into three groups (Kinesio Taping and exercises, Kinesio Taping only and exercises only). The outcomes assessed in this study were pain intensity, disability and lumbar muscle activation measured by electromyography. No between-group differences were observed. Another study17 compared the effect of Kinesio Taping versus the control procedure of the present trial (Kinesio Taping without convolutions) for the outcomes pain, disability and range of motion for trunk flexion. People Modulators received only one application of the tape, which remained in situ for Nutlin-3a cell line one week. This study also did not identify any differences in favour of the Kinesio Taping. We do not know of any studies that have evaluated the Kinesio Taping Method using the global perceived effect scale. There are five published systematic reviews15, 28, 29, 30 and 31 evaluating the effectiveness of Kinesio Taping; one

specifically targeted the treatment and prevention of sports injuries,15 two examined different clinical conditions,29 and 30 and two looked at musculoskeletal conditions.28 and 31 However, none of these reviews found any clinically worthwhile benefits for this intervention. The studies compared Kinesio Taping with a range of treatments, as well as with no treatment selleck inhibitor and placebo. These studies were, on average, of moderate methodological quality, with small sample sizes and very small follow-up periods. Regardless of the comparisons used (as well as the outcomes investigated), the results of clinical trials conducted so far have shown no difference or found just a trivial effect in favour of Kinesio Taping. Our group conducted the most updated systematic review32 with the greatest number of

clinical trials relevant to musculoskeletal conditions and our conclusions were similar to the existing reviews. The results of the present study challenge the importance of the presence of convolutions in Kinesio Taping for effectiveness of treatment in people with chronic low back pain. According to the creators of the Kinesio Taping Method14 these from convolutions increase blood and lymphatic flow, and aid in reducing pain. Therefore, applying proper tension is one of the key factors for effective treatment.14 However, the outcome with convolutions was not superior to the control group and so the improvement seen in both groups cannot be due to tape tension. The results of the present study challenge the theory that these convolutions are part of the mechanism. To date, the present study is the largest clinical trial conducted on the effectiveness of Kinesio Taping.

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