This network involves a set of regulated transcription factors th

This network involves a set of regulated transcription factors that crosstalk with physiological signaling. The knowledge thus acquired paves the way for the genetic engineering of oilseed crops dedicated to food applications or green chemistry. (C) 2010 Elsevier Ltd. All rights reserved.”
“Objectives: learn more Thoracic endovascular aortic repair (TEVAR) has been gaining popularity for the treatment of thoracoabdominal aortic aneurysm (TAAA). We used a nonvoluntary database to examine national trends and regional/hospital variations in the use of TEVAR and open thoracic aortic repair (OTAR) for TAAA.

Methods: From the 2005-2008 Nationwide

Inpatient Sample database, we identified all patients with the diagnosis of TAAA who were treated with TEVAR or OTAR. Rates of these procedures were compared between years, across geographic regions, and between hospitals of various bed sizes.

Results: Over the study period, the rate of OTAR remained relatively stable TPX-0005 manufacturer (range, 7.5/100 patients in 2005 to 10.1/100 patients in 2008; P = .26), whereas the rate of TEVAR increased dramatically (range, 1.4/100 patients in 2005 to 6.3/100 patients in 2008; P<.0001). In 2008, 29%(211) of all TEVAR procedures and 11%(130) of all OTAR

procedures were performed in western regions of the United States (P = .03). Additionally, 13%(95) of all TEVAR procedures and 3%(35) of all OTAR procedures were performed in smaller hospitals (P<.0001).

Conclusions: The use of TEVAR for TAAA repair increased significantly over the study period, whereas OTAR rates remained relatively stable. Our findings suggest that more patients who were otherwise not surgical candidates or did not have traditional

surgical indications for OTAR were treated with TEVAR, most commonly in regions or hospitals where OTAR is less often performed. Given the complexity of TAAA cases, these results may have significant Lumacaftor price implications for patient safety in the current era of heightened health care scrutiny. (J Thorac Cardiovasc Surg 2012;144:612-6)”
“BACKGROUND

Survivors of sexual violence have high rates of depression, anxiety, and post-traumatic stress disorder (PTSD). Although treatment for symptoms related to sexual violence has been shown to be effective in high-income countries, evidence is lacking in low-income, conflict-affected countries.

METHODS

In this trial in the Democratic Republic of Congo, we randomly assigned 16 villages to provide cognitive processing therapy (1 individual session and 11 group sessions) or individual support to female sexual-violence survivors with high levels of PTSD symptoms and combined depression and anxiety symptoms. One village was excluded owing to concern about the competency of the psychosocial assistant, resulting in 7 villages that provided therapy (157 women) and 8 villages that provided individual support (248 women).

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