CsA: 138 +/- 4 mmHg, P < 0.05) and FMD was
higher in SRL compared with CsA (SRL: 13.1 +/- 0.9 vs. CsA: 9.9 +/- 0.9%, P < 0.05) without any difference for hyperaemia, endothelium-independent dilatation and GFR (SRL: 66.7 +/- 1.05 vs. CsA: 67.5 +/- 1.22 ml/min). Our results demonstrate that a CNI-free regimen based on SRL and MMF prevents conduit artery endothelial dysfunction compared with CsA and MMF in kidney recipients suggesting a beneficial arterial wall effect that may also contribute to the decrease in systolic blood pressure.”
“The spectral linewidth of terahertz oscillators using resonant tunneling Idasanutlin diodes and their coupled arrays is theoretically analyzed. The theoretical linewidths of single oscillators are consistent with the measured results. The linewidth of resonant tunneling diodes is considerably broader than that of terahertz quantum cascade lasers because of lower output power and the existence of shot noise. The theoretical analysis for a single oscillator is extended to a coupled array, and it is shown
that the linewidth of a coupled N-element array reduces to 1/N that of a single oscillator, if the frequency deviation among the elements is small. With an Selleckchem RG-7112 increasing frequency deviation, the linewidth increases and exceeds that of a single oscillator. The linewidth also increases with the imaginary part of the coupling admittance between the elements. (C) 2010 American Institute of Physics. RSL3 chemical structure [doi: 10.1063/1.3460642]“
“Purpose: To compare the diagnostic performance and radiation doses of dual-source and 64-section computed tomographic (CT) coronary angiography for the diagnosis of significant coronary stenoses in patients with heart rates of 65 beats/min or less.
Materials and Methods: This retrospective study had local ethics committee approval; all patients gave written informed consent. Two hundred patients with heart rates of 65 beats/min or less were enrolled; 100 underwent dual-source and 100 underwent 64-section CT coronary angiography. Two blinded observers independently assessed image quality of all coronary segments by using a four-point scale and searched for significant (>50%)
stenoses in each segment. Catheter angiography was used as the reference standard. Image noise was measured in the ascending aorta. Radiation doses were calculated.
Results: No significant differences were found regarding sex, age, body weight, cardiovascular risk profile, prevalence of stenosis, mean and variability of heart rate, Agatston score, and image noise (all P>.1) between patients in both CT coronary angiography groups. No significant difference was found in the rate of nonassessable coronary segments between dual-source (1.0%, 14 of 1405) and 64-section CT coronary angiography (1.8%, 25 of 1387; P = .08). Motion artifacts occurred significantly more often in 64-section (21 of 25) versus dual-source (five of 14, P = .004) CT coronary angiography.