Monthly Archives: August 2016

Evidence suggests cross-talk between IGF-1R and EGFR, which might

Evidence suggests cross-talk between IGF-1R and EGFR, which might be crucial for the mitogenic and transforming activity of EGFR. More specifically, the IGF-1 downstream signaling cascade is thought to induce EGFR independent PIK3CA and AKT activity, which might be another … Continue reading

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2013 Available at:

2013. Available at: . Date accessed: 12 Mar. 2013. Firstly, I thank Seifsafari, Firoozabadi, Ghanizadeh, and Salehi for their interesting and relevant study.1 In this they conclude that somatic symptoms have a central part in the presentation of depressed patients … Continue reading

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Cetuximab is a monoclonal antibody (MoAb) against the ligand-bind

Cetuximab is a monoclonal antibody (MoAb) against the ligand-binding domain of the EGFR evaluated in combination with gemcitabine in a randomized phase III trial. However, the study failed to demonstrate the superiority of the combination over the gemcitabine control arm … Continue reading

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21

Biochemical studies have demonstrated a direct interac

21 Biochemical studies have demonstrated a direct interaction of clarithromycin and its chief metabolite, 14-hydroxyclarithromycin, with 50S ribosomal subunits isolated from H. pylori.22,23 The antibacterial activity of clarithromycin is better than that of erythromycin. One reason for such a difference … Continue reading

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10 Histologically, both are composed of nests of basaloid cells w

10 Histologically, both are composed of nests of basaloid cells within the dermis. Although these differences are distinguishable in the majority of cases, there are cases in which distinction is difficult, not least in small and superficial biopsy specimens.9 The … Continue reading

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It is a progressive process, and not categorized as a disease, un

It is a progressive process, and not categorized as a disease, unless it interferes with the normal function of the organs. Diabetes mellitus and Alzheimer’s disease (AD) are the most prevalent ageing diseases, and are examples of the tissue impairment … Continue reading

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A sonic explosion can occur, releasing a large amount of energy,

A sonic explosion can occur, releasing a large amount of energy, although for very short (μm) distances. Tissues and cells in the vicinity can be damaged. Cavitation is the responsible mechanism for the disintegrations of stones in lithotripsy. Chemical effects, … Continue reading

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1995;

Kirsch 1996; DeFelice 1997; Gilula 2007; O’Connell

1995; Kirsch 1996; DeFelice 1997; Gilula 2007; O’Connell et al. 2010 for review and meta-analyses). The majority of controlled studies have evaluated the efficacy of CES for treatment of anxiety, although most were performed in nonclinical samples (Klawansky et al. … Continue reading

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81 A total of 20 variants were observed, 17 of which were locate

81 A total of 20 variants were observed, 17 of which were located in the coding region. Two variants in the N-terminal and five in the C-terminal caused an amino acid exchange (Figure 3b), which amounted to a much higher … Continue reading

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RefSeq (mRNA) is the official number of the most relevant gene pr

RefSeq (mRNA) is the official number of the most relevant gene product. Exon no. is the number of exons. mRNA (ORF) is the length of the mRNA and within brackets the length of the open reading frame also counting the … Continue reading

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