Monthly Archives: April 2017

4, p < 0.01) and SYM (t26 = 1.7, p < 0.05) groups. Paired t tests demonstrated a significant reward bias in the PRE group (t13 = 4.8, p < 0.001), but not in the CON and SYM groups (t13 = 0.6, p > 0.1 and … Continue reading →

Agenesis of the corpus callosum is found in 1 in 4,000 individuals and is associated with a wide range of developmental defects and syndromes (Paul et al., 2007). Many affected patients have mental retardation, seizures, or autism spectrum disorders. There are … Continue reading →

Copulation typically lasts ∼20 min (Jagadeeshan and Singh, 2006). For the first several minutes of this period, wild-type pairs may move forward or adjust positions, but for the remainder of this time the flies remain essentially motionless. Copulation in prt1 mutants … Continue reading →

Healthy-brain connectivity networks were recomputed using this new atlas for the purpose of seeding tracts. In order to perform statistically rigorous hypothesis testing, we adopted a simple correlation approach. The t-statistic of atrophy within each disease group and for all … Continue reading →

An important hallmark of C3-C4 propriospinal neurons is the establishment of a bifurcating axonal trajectory (Figure 8A). Descending collaterals establish synaptic connections to motor neurons at C6-T1 and interneurons, whereas ascending axon collaterals extend to the lateral reticular nucleus (LRN), which … Continue reading →

05, circular ANOVA). Previous V4 studies have shown that selective attention to a single stimulus inside an RF increases not only firing rates, but also gamma-band LFP power, MUA-LFP and MUA-MUA gamma-band coherence (Fries et al., 2001b, Fries et al., 2008 and Gregoriou et al., … Continue reading →

, 2001 and Millar et al., 2000). Additional linkage studies with DISC1 mutations further support its role in influencing risk for psychosis and autistic spectrum disorders ( Chubb et al., 2008). Functional studies in animal models suggest that DISC1 plays a multifaceted role in … Continue reading →

, 2009). Paip2a−/− mice performed better in this task than WT littermates ( Figure 2F). We found no differences between the two genotypes in the novel object recognition task ( Figure 2G), which examines recognition memory. Taken together, our data indicate that … Continue reading →

Of roughly 140 miRNA expressed in five regions of the rat brain (cortex, hippocampus, cerebellum, brainstem, and olfactory bulb), the majority (79%–97%) were also found in synaptosomes from each region (Figure 2D). While a significant number (up to ∼25%) of the … Continue reading →

The findings of reduced GS-7340 cost DA soma size and DA output are consistent with earlier reports that chronic morphine decreases levels of neurofilament proteins in VTA and impairs axoplasmic transport from VTA to NAc (Beitner-Johnson et al., 1992 and Beitner-Johnson and Nestler, … Continue reading →