The leading causes for relaparotomy was bleeding (70%) and burst abdomen (8.8%). Hysterectomy was performed in 31.3% of
the patients. Conclusion: Risk factors for relaparotomy after CS are previous CS, severe preeclampsia, placenta previa, uterine rupture, placental abruption, cervical tear and PPH. Experienced obstetricians should be involved in such cases and the possibility for complications including relaparotomy should be emphasized.”
“Paeonol is a micromolecular phenolic compound and it is the main component of Chinese herbal medicine that has been isolated from the root bark of Paeonia moutan. Paeonol is identified to have various physiological activities. In this study the antitumor activity and the possible mechanisms of paeonol were investigated in mice bearing EMT6 breast cancer model. The results showed that paeonol (150 mg/kg and 300 mg/kg) effectively reduced the weight of EMT6 breast tumor. Compared with the control group, paeonol JNJ-26481585 significantly CP-456773 molecular weight increased the number of tumor cells in G0/G1 phase, increased the number of cells in apoptosis and decreased the number of cells in S phase and G2/M, inhibited the expression of mutant p53, Bcl-2 and C-erbB-2 protein. The mechanisms of paeonol of antitumor effects might be associated with inhibition of tumor cells in G0/G1 phage, inducing cell apoptosis and inhibiting the expression of mutant
p53, Bcl-2 and C-erbB-2 protein.”
“Objective: To report our experience in the selection of newborns candidate to therapeutic hypothermia. Methods: Retrospective study involving 47 newborns suffering from perinatal asphyxia from January 2008 to September 2011. Results: Thirty-five of 47 newborns admitted to our hospital fulfilled metabolic and neurological criteria for recruitment and were cooled. aEEG was carried out
Entinostat mw in 26 of them and resulted always abnormal. In three of the 12 newborns with only metabolic criteria, aEEG was moderately abnormal. They were cooled and their outcome (evaluated by General Movements and Griffiths Mental Development Scales for children aged 0-2 years) is good. Three additional newborns who only met the metabolic criterion reached our hospital after the therapeutic window for hypothermia and exhibited seizures; their outcome is poor. Conclusions: In our experience, the inclusion of aEEG in the entry criteria would not have precluded newborns with neurological criteria from cooling. On the contrary, without an early aEEG, we would have excluded from hypothermia infants with moderate hypoxic-ischemic encephalopathy without precocious neurological signs who exhibited only the metabolic criterion, but with abnormal aEEG. If further studies will confirm that early aEEG might identify newborns suitable for cooling even in the absence of clinical signs, a revision of the entry criteria should be considered.”
“”"Antioxidant Activity of Three Species of Eugenia (Myrtaceae)”". Extracts of Eugenia brasiliensis, E.