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“The purpose of this study was to evaluate the surface roughness (R(a)) and microscopic change to irradiated dental implant surfaces in vitro and ultimately to determine the proper pulse energy power and application time for the clinical use of Er:YAG lasers. Anodic oxidized surface implants and sand-blasted, large-grit, and acid-etched (SLA) surface implants were used. Each experimental group of implant surfaces included ten implants. Nine implants were used for the laser irradiation test groups
and one for the control group. Each test group was equally divided into three subgroups by irradiated pulse energy power. Using an Er: YAG laser, each S3I-201 clinical trial subgroup
of anodic oxidized surface implants was split into 60-, 100-, and 140-mJ/pulse groups, with each subgroup of SLA surface implants irradiated with a 100-, 140-, or 180-mJ/pulse. Three implants in every test subgroup were respectively irradiated for 1, 1.5, and 2 min. The Ra values for each specimen were recorded and every specimen was observed by SEM. Irradiation by Er: YAG laser led to a decrease in implant surface roughness that was not statistically significant. In anodic oxidized surfaces, the oxidized layer peeled off of the surface, and cracks appeared on implant surfaces in the 100- and 140-mJ/pulse subgroups. However, with SLA surfaces, no significant change in surface texture could be found on any implant surface in the 100- and Selleck SNX-5422 140-mJ/pulse subgroups. The melting and fusion phenomena of implant surfaces were observed with all application times with 180 mJ/pulse irradiation.
learn more The SLA implant surfaces are stable with laser intensities of less than 140 mJ/pulse and an irradiation time of less than 2 min. The anodic oxidized surfaces were not stable with laser intensities of 100 mJ/pulse when an Er: YAG laser was used to detoxify implant surfaces.”
“Ami. To describe a histologic scoring system for murine osteoarthritis (OA) that can be applied universally to instability, enzymatic, transgenic and spontaneous OA models
Methods Scientists with expertise in assessing murine OA histopathology reviewed the merits and drawbacks of methods described in the literature A semi-quantitative scoring system that could reasonably be employed in any basic cartilage histology laboratory was proposed This scoring system was applied to a set of 10 images of the medial tibial plateau and femoral condyle to yield 20 scores These images were scored twice by four experienced scorers (CL, SG, MC, TA), with a minimum time interval of I week between scores to obtain intra-observer variability.