Therefore, patients with detectable carotid plaque in panoramic radiographs require referral to their physician for further investigation. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009; 108: 600-603)”
“BACKGROUND: Randomized controlled trials report short- and medium-term outcomes following percutaneous coronary intervention
(PCI), but their applicability to the general population is not known. Data regarding the long-term clinical outcomes of patients undergoing PCI are lacking.
OBJECTIVE: To determine the long-term outcomes of ‘all-comers’ undergoing PCI at a large-volume tertiary cardiac referral centre.
METHODS: A total of 12,662 consecutive patients undergoing an index procedure and entered Bromosporine into the University Health Network’s (Toronto, Ontario) prospective registry between selleck products April 2000 and September 2007 were identified. In-hospital outcomes were assessed. Follow-up data were obtained through linkage to a provincial registry. Kaplan-Meier analysis was performed to calculate unadjusted survival rates, and Cox multiple regression analysis identified independent predictors of late mortality,
major adverse cardiac events and all cardiovascular events.
RESULTS: The population included a relatively high-risk patient cohort, with 19% older than 75 years of age, 28% with diabetes, 61% with multivessel disease and 1.3% in cardiogenic MI-503 shock. Urgent procedures comprised 53% of all cases. The all-cause mortality rate at seven years follow-up was 10.6%. Repeat PCI occurred in 14.2% of patients, and coronary artery bypass grafting in 4.2%. Men showed a significant unadjusted survival advantage compared with women. Procedural characteristics
such as incomplete revascularization and residual stenosis, in addition to established risk factors, were predictors of poorer long-term outcomes. Cardiogenic shock was the strongest predictor of late mortality.
CONCLUSION: In the present large registry of ‘all-comers’ for PCI, long-term major adverse cardiac event rates were low and consistent with outcomes from randomized controlled trials. These data reflect a large cohort in real-world clinical practice, and may help clinicians further characterize and better treat high-risk patients who are undergoing PCI.”
“BACKGROUND: Acute cellular rejection and lymphocytic bronchiolitis can impair allograft function after lung transplant (LTx). Both may be refractory to corticosteroid treatment. We hypothesized that bronchoalveolar lavage (BAL) neutrophilia may be increased in either acute rejection or lymphocytic bronchiolitis or may increase with increasing histologic severity.
METHODS: All consecutive BAL with subsequent transbronchial biopsy (TBB) specimens, performed in 339 LTx recipients from 2001 to 2008, were retrospectively analyzed.