Transpl Infect Dis 2011: 13: 213-215 All rights reserved “

Transpl Infect Dis 2011: 13: 213-215. All rights reserved.”
“We report on a 51-year old heart transplant recipient in whom a pacing lead fragment of his old implantable cardioverter-defibrillator (ICD) had been detected in the left ventricle following successful heart transplantation. The patient was transplanted after click here 5 weeks on high urgent status. A postoperative routine chest X-ray and a subsequent cardiac three-dimensional (3D) computed tomography scan showed a metallic foreign body

bending during systole below the posterior mitral valve leaflet within the left ventricle of the heart transplant. Transarterial extraction therapy was planned and the femoral artery was cannulated in the usual fashion. An 8F snare catheter was directed into the left ventricle under fluoroscopic guidance. Successful extraction

revealed a 3-cm, uncoated ICD fragment (diameter = 0.025 in.). Following extraction of the fragment echocardiography showed mild mitral regurgitation but no Momelotinib inhibitor further adverse events occurred. The patient was discharged 2 days later. Transarterial fragment extraction using a snare catheter is a feasible, minimally invasive procedure in this clinical scenario. Careful inspection of all explanted hardware is strongly recommended to ensure that no portion of an ICD lead is left behind.”
“Crohn’s disease is a chronic inflammatory condition affecting the gastrointestinal tract at any point from the mouth to the rectum. Patients may experience diarrhea, abdominal pain, fever, weight loss, abdominal masses, and anemia. Extraintestinal manifestations of Crohn’s disease include osteoporosis, inflammatory arthropathies, scleritis, nephrolithiasis, cholelithiasis, and erythema nodosum. Acute phase reactants, such as C-reactive protein level and erythrocyte sedimentation rate, are often increased with

inflammation and may correlate with disease activity. Levels of vitamin B, folate, albumin, prealbumin, and vitamin D can help assess nutritional status. Colonoscopy with ileoscopy, capsule endoscopy, GSI-IX computed tomography enterography, and small bowel follow-through are often used to diagnose Crohn’s disease. Ultrasonography, computed axial tomography, scintigraphy, and magnetic resonance imaging can assess for extraintestinal manifestations or complications (e.g., abscess, perforation). Mesalamine products are often used for the medical management of mild to moderate colonic Crohn’s disease. Antibiotics (e.g., metronidazole, fluoroquinolones) are often used for treatment. Patients with moderate to severe Crohn’s disease are treated with corticosteroids, azathioprine, 6-mercaptopurine, or anti-tumor necrosis factor agents (e.g., infliximab, adalimumab). Severe disease may require emergent hospitalization and a multidisciplinary approach with a family physician, gastroenterologist, and surgeon. (Am Fam Physician. 2011;84(12):1365-1375. Copyright (C) 2011 American Academy of Family Physicians.

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