The number of recovered oocytes, obtained embryos, transferred embryos, see more peak of estradiol on the day HCG administration and OHSS were significantly higher in group A. Significantly more patients in control group had embryos for cryopreservation. There were no significant difference in clinical pregnancy
rate and ongoing pregnancy rate between two groups.
Clomiphene + delayed low dose gonadotropin + flexible GnRH – antagonist stimulation is an acceptable alternative protocol for IVF in patients with regularly menstruation.”
“Soy protein concentrate was grafted with ethylmethacrylate using ascorbic acid/potassium persulphate as a redox initiator. Different reaction parameters, such as reaction time, reaction temperature, IPI 145 solvent amount, initiator ratio, and pH, and monomer concentration were optimized to get maximum graft yield (134.12%). The graft copolymer formed was characterized by Fourier transform infrared spectrophotometer, X-ray diffraction, and scanning electron microscope techniques. Thermogravimetric analysis, differential thermal analysis, and differential thermogravimetric analysis studies showed that graft copolymer was thermally more stable than the backbone. Thermal decomposition studies indicated that the rate of weight loss per minute was found more in case of backbone when compared
with that of graft copolymer. Further, graft copolymer was also found more resistant toward acid-base attack and was found to be more water repellent. (C) 2010 Epigenetics inhibitor Wiley Periodicals, Inc. J Appl Polym
Sci 120: 2183-2190, 2011″
“Background: Rapid and sensitive detection of KRAS mutation is needed to maximize the benefits for patients who are being treated with monoclonal antibodies to target the epidermal growth factor receptor in colorectal cancer. The aim of this study is to evaluate the efficacy of the peptide nucleic acid clamp real-time PCR (PCqPCR) as compared to that of direct sequencing (DS) between using fresh colorectal cancer tissue and the matched formalin-fixed and paraffin-embedded (FFPE) colorectal cancer tissue. Methods: The efficacy of PCqPCR was evaluated and compared with that of DS using fresh tissue and matched FFPE tissue from 30 cases of colorectal cancer. Results: PCqPCR is more sensitive than DS for detecting KRAS mutation. PCqPCR detected 1% of mutants in 1 ng DNA. PCqPCR detected mutation in 1% of mutant cells, while DS barely detected, by manual reading, that in 20-50% of mutant cells. In the clinical samples, PCqPCR detected KRAS mutation in 60.0% while DS detected KRAS mutation in 53.3% of the colorectal cancers. The two methods showed a 100% concordance rate for detecting KRAS mutation between the fresh tissue and FFPE tissue. Conclusions: The PCqPCR method is efficiently applicable for the detection of KRAS mutation in a clinical setting.